BDBM50568954 CHEMBL4855080

SMILES COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1OCCCCC(=O)Nc1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=ZKOBDTJAZIVUSK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50568954   

TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50568954(CHEMBL4855080)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR T790M mutant (669 to 1210 residues) expressed in baculovirus expression system using pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50568954(CHEMBL4855080)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged EGFR (669 to 1210 residues) expressed in baculovirus expression system using peptide as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed