BDBM50569530 CHEMBL4860473::US11452717, Compound TableB-2.198

SMILES O=C(NCc1ccncc1)Nc1ccc(cc1)S(=O)(=O)Nc1ccccc1

InChI Key InChIKey=LHRRQCPVFVGKNY-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50569530   

TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM50569530(CHEMBL4860473 | US11452717, Compound TableB-2.198)
Affinity DataEC50:  1.05E+3nMAssay Description:NAMPT reaction was performed in 50 mM HEPES, pH 7.5, containing 5 mM MgCl2, 0.1% Prionex, 0.005% Tween 20, and 1 mM TCEP at room temperature in Grein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM50569530(CHEMBL4860473 | US11452717, Compound TableB-2.198)
Affinity DataEC50:  410nMAssay Description:Activation of human NAMPTMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed