BDBM50569779 CHEMBL4871799

SMILES CCN(C(=O)c1cc(C(C)C)c(O)cc1O)c1cccnc1

InChI Key InChIKey=CFNZXIBOGQPSNR-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50569779   

TargetCytochrome P450 3A4(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50569779(CHEMBL4871799)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using testosterone as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50569779(CHEMBL4871799)
Affinity DataIC50: 3.23E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50569779(CHEMBL4871799)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using S-mephenytoin as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50569779(CHEMBL4871799)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCytochrome P450 2B6(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50569779(CHEMBL4871799)
Affinity DataIC50: 3.72E+4nMAssay Description:Inhibition of CYP2B6 in human liver microsomes using bupropion as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50569779(CHEMBL4871799)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50569779(CHEMBL4871799)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2C8 in human liver microsomes using amodiaquine as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50569779(CHEMBL4871799)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50569779(CHEMBL4871799)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of HSP90 (unknown origin) assessed as competition of fluorescently labelled geldanamycin binding after 2 hrs by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed