BDBM50569817 CHEMBL4873127

SMILES CCCCC(Oc1cccc(Cl)c1Cl)c1nc(N)nc(n1)N1CCN(C)CC1

InChI Key InChIKey=KPRWGLQDBYNALG-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50569817   

Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50569817(CHEMBL4873127)
Affinity DataKi:  73nMAssay Description:Binding affinity to human 5HT6 receptor expressed in HEK293 cells assessed as inhibition constant incubated for 1 hr radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50569817(CHEMBL4873127)
Affinity DataKi:  73nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in HEK293 cells incubated for 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50569817(CHEMBL4873127)
Affinity DataKi:  470nMAssay Description:Displacement of [3H]-Ketanserin from human 5-HT2A receptor expressed in CHO-K1 cells incubated for 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50569817(CHEMBL4873127)
Affinity DataKi:  470nMAssay Description:Binding affinity to human 5HT2A receptor expressed in CHO-K1 cells assessed as inhibition constant incubated for 1 hr radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCholinesterase(Horse)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50569817(CHEMBL4873127)
Affinity DataIC50: 500nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition and measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50569817(CHEMBL4873127)
Affinity DataKi:  506nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50569817(CHEMBL4873127)
Affinity DataKi:  506nMAssay Description:Binding affinity to human dopamine 2 receptor expressed in HEK293 cells assessed as inhibition constant incubated for 1 hr radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50569817(CHEMBL4873127)
Affinity DataKi:  5.27E+3nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7R expressed in human HEK293 cells incubated for 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50569817(CHEMBL4873127)
Affinity DataKi:  5.27E+3nMAssay Description:Binding affinity to human 5HT7 receptor expressed in HEK293 cells assessed as inhibition constant incubated for 1 hr radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed