BDBM50569826 CHEMBL4868911

SMILES CN1CCN(CC1)c1nc(N)nc(CCCOc2ccc(Cl)c(Cl)c2)n1

InChI Key InChIKey=RACXIEAYJFKQIR-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50569826   

TargetD(2) dopamine receptor(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50569826(CHEMBL4868911)
Affinity DataKi:  356nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cells measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50569826(CHEMBL4868911)
Affinity DataKi:  906nMAssay Description:Displacement of [3H]-Ketanserin from human 5-HT2A receptor expressed in CHO-K1 cells incubated for 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50569826(CHEMBL4868911)
Affinity DataKi:  1.06E+3nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in HEK293 cells incubated for 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50569826(CHEMBL4868911)
Affinity DataKi:  4.88E+3nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7R expressed in human HEK293 cells incubated for 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed