BDBM50569922 CHEMBL4863942

SMILES CCOc1cc2[C@H](Cc3c[nH]c4ccc(C)cc34)N(CCc2cc1OC)C=O

InChI Key InChIKey=IJUPMPZUBYVZGZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50569922   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50569922(CHEMBL4863942 | US12145923, Compound (S)-C17)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant human PDE4D (83 to 416 residues) expressed in Escherichia coli BL21 (DE3) assessed as hydrolysis of [3H]-cAMP measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50569922(CHEMBL4863942 | US12145923, Compound (S)-C17)
Affinity DataIC50: 1.10E+6nMAssay Description:The scintillation Proximity Assay (SPA) method was used to determine the inhibitory effect of compounds on the activity of PDE4D catalytic domain. Hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent