BDBM50570263 CHEMBL4849570

SMILES Clc1cc(cnc1C#N)N1C(=S)N(c2ccc(OC3CCNCC3)nc2)C2(CCC2)C1=O

InChI Key InChIKey=ZXSHKSIAPKOCNB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50570263   

TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50570263(CHEMBL4849570)
Affinity DataIC50: 47nMAssay Description:Antagonist activity at AR F877L mutant (unknown origin) transfected in human LNCAP cells cotransfected with ARE-LUC incubated for 20 to 24 hrs in pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50570263(CHEMBL4849570)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at AR wild-type (unknown origin) transfected in human LNCAP cells cotransfected with ARE-LUC incubated for 20 to 24 hrs in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed