BDBM50570304 CHEMBL4860925

SMILES CNc1nc(C)c(-c2nc(Nc3cccc(N4CCN5CCC4CC5)c3)ncc2C)s1

InChI Key InChIKey=RSTOVEUALSXORR-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50570304   

TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
University of Nottingham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50570304BDBM50570304(CHEMBL4860925)
Affinity DataKi:  10nMAssay Description:Inhibition of recombinant human full length CDK9/Cyclin T1 using KTFCGTPEYLAPEVRREPRILSEEEQEMFRDFDYIADWC as substrate incubated for 40 mins in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
University of Nottingham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50570304BDBM50570304(CHEMBL4860925)
Affinity DataKi:  546nMAssay Description:Inhibition of recombinant human full length CDK7/Cyclin H using peptide as substrate incubated for 40 mins in presence of [gamma-33P]-ATP by scintill...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
University of Nottingham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50570304BDBM50570304(CHEMBL4860925)
Affinity DataKi:  1.17E+3nMAssay Description:Inhibition of recombinant human full length CDK1/Cyclin B using histone H1 as substrate incubated for 40 mins in presence of [gamma-33P]-ATP by scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
University of Nottingham

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50570304BDBM50570304(CHEMBL4860925)
Affinity DataKi:  1.25E+3nMAssay Description:Inhibition of recombinant human full length CDK2/Cyclin A using histone H1 as substrate incubated for 40 mins in presence of [gamma-33P]-ATP by scint...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed