BDBM50570366 CHEMBL4877760

SMILES CCCCCCCCCCCCCCOCC(CNC(=O)CCCCCN)OCCCCCCCCCCCCCC

InChI Key InChIKey=GZKHIOSBPWAHLA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50570366   

TargetToll-like receptor 2(Human)
Neuropore Therapies

Curated by ChEMBL
LigandPNGBDBM50570366(CHEMBL4877760)
Affinity DataIC50: 2.00E+4nMAssay Description:Antagonist activity at human TLR2 expressed in HEK-Blue cells assessed as inhibition of Pam3CSK4-induced TLR2/TLR1 activation by measuring decrease i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Neuropore Therapies

Curated by ChEMBL
LigandPNGBDBM50570366(CHEMBL4877760)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human TLR2 expressed in HEK-Blue cells assessed as inhibition of Pam2CSK4-induced TLR2/TLR6 activation by measuring decrease i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Neuropore Therapies

Curated by ChEMBL
LigandPNGBDBM50570366(CHEMBL4877760)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of TNFalpha (unknown origin) in HEK-Blue-hTLR2 cells assessed as inhibition of TNFalpha-induced NFkappaB activation pretreated for 2 hrs f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed