BDBM50570367 CHEMBL4862067

SMILES CCCCCCCCCCCCCCOCC(CNC(=O)[C@H]1CC[C@H](N)CC1)OCCCCCCCCCCCCCC

InChI Key InChIKey=CXEMIDKFVWNRRV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50570367   

TargetToll-like receptor 2(Human)
Neuropore Therapies

Curated by ChEMBL
LigandPNGBDBM50570367(CHEMBL4862067)
Affinity DataIC50: 3.70E+3nMAssay Description:Antagonist activity at human TLR2 expressed in HEK-Blue cells assessed as inhibition of Pam3CSK4-induced TLR2/TLR1 activation by measuring decrease i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetToll-like receptor 2(Human)
Neuropore Therapies

Curated by ChEMBL
LigandPNGBDBM50570367(CHEMBL4862067)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human TLR2 expressed in HEK-Blue cells assessed as inhibition of Pam2CSK4-induced TLR2/TLR6 activation by measuring decrease i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetTumor necrosis factor(Human)
Neuropore Therapies

Curated by ChEMBL
LigandPNGBDBM50570367(CHEMBL4862067)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of TNFalpha (unknown origin) in HEK-Blue-hTLR2 cells assessed as inhibition of TNFalpha-induced NFkappaB activation pretreated for 2 hrs f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed