BDBM50570591 CHEMBL4873295

SMILES COc1cccc(CNC[C@@H](O)[C@H](Cc2ccccc2)NC(=O)C(c2ccccc2)c2ccccc2)c1

InChI Key InChIKey=PPHOEEHPKILQIL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50570591   

TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50570591(CHEMBL4873295)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine as substrate preincubated for 5 mins followed by substrate addition and measured after 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetSodium- and chloride-dependent GABA transporter 3(Mouse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50570591(CHEMBL4873295)
Affinity DataIC50: 3.31E+4nMAssay Description:Inhibition of mouse GAT4 expressed in HEK293 cell line assessed as reduction in [3H]GABA uptake incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed