BDBM50570679 CHEMBL4874716

SMILES ONC(=O)c1ccc(CN2c3ccccc3Sc3ccc(cc23)C(=O)Nc2ccc(Br)cn2)cc1

InChI Key InChIKey=IJBHQQMTDZNJTA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50570679   

TargetHistone deacetylase(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50570679(CHEMBL4874716)
Affinity DataIC50:  30nMAssay Description:Inhibition of HDAC in human HeLa nuclear extracts using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50570679(CHEMBL4874716)
Affinity DataIC50:  2.28E+3nMAssay Description:Inhibition of N-terminal GST-tagged and C-terminal His-tagged human HDAC4 (627 to 1084 residues) expressed in baculovirus infected Sf9 cells using Bo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50570679(CHEMBL4874716)
Affinity DataIC50:  163nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 9(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50570679(CHEMBL4874716)
Affinity DataIC50:  850nMAssay Description:Inhibition of C-terminal His-tagged human HDAC9 (604 to 1066 residues) expressed in baculovirus-infected Sf9 cells using Boc Lys(TFA)-AMC as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50570679(CHEMBL4874716)
Affinity DataIC50:  370nMAssay Description:Inhibition of N-terminal GST-tagged human HDAC7 (518 to end residues) expressed in baculovirus-infected Sf9 cells using Boc Lys(TFA)-AMC as substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed