BDBM50570790 CHEMBL4847971
SMILES COc1ncc(cc1NS(C)(=O)=O)-c1cc(O[C@@H]2CCN(C2)C(=O)C2CC2)cc2C(=O)NCc12
InChI Key InChIKey=GJISQLYNRBQOQM-OAHLLOKOSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50570790
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataIC50: 0.540nMAssay Description:Inhibition of PI3Kdelta (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of PI3Kgamma (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of PI3Kbeta (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Merck
Curated by ChEMBL
Merck
Curated by ChEMBL
Affinity DataIC50: 315nMAssay Description:Inhibition of PI3Kalpha (unknown origin) by HTRF assayMore data for this Ligand-Target Pair