BDBM50570842 CHEMBL4868811::US11918568, Example 13

SMILES Cn1nccc1-c1nc2ccc(NC(=O)NCc3ccncc3)cn2n1

InChI Key InChIKey=BMYQZNNIBQKDEI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50570842   

TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM50570842(CHEMBL4868811 | US11918568, Example 13)
Affinity DataEC50:  180nMAssay Description:The NAMPT enzyme assay was conducted in accordance with the method of Formentini et al. (Formentini L. et al., Biochemical Pharmacology 77 (2009) 161...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Sanford Burnham Prebys Medical Discovery Institute

US Patent
LigandPNGBDBM50570842(CHEMBL4868811 | US11918568, Example 13)
Affinity DataEC50:  180nMAssay Description:Activation of human NAMPT assessed as increase in NMN production by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed