BDBM50570944 CHEMBL4866245

SMILES CC(C)NC(=O)c1cc(cnc1N)-c1ccc(NC(=O)Cc2ccccc2)cc1C

InChI Key InChIKey=QXFDNMNTISNJLZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50570944   

TargetEukaryotic translation initiation factor 2 subunit 1(Homo sapiens)
Hibercell

Curated by ChEMBL
LigandPNGBDBM50570944(CHEMBL4866245)
Affinity DataIC50:  307nMAssay Description:Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Hibercell

Curated by ChEMBL
LigandPNGBDBM50570944(CHEMBL4866245)
Affinity DataIC50:  73nMAssay Description:Inhibition of human His-tagged PERK expressed in Escherichia coli assessed as eIF2alpha phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed