BDBM50570949 CHEMBL4848921

SMILES CC(C)NC(=O)c1cc(cnc1N)-c1ccc(NC(=O)[C@@](C)(O)c2ccccc2)cc1C

InChI Key InChIKey=DZDRNVJHVMKPKJ-VWLOTQADSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50570949   

TargetEukaryotic translation initiation factor 2 subunit 1(Homo sapiens)
Hibercell

Curated by ChEMBL
LigandPNGBDBM50570949(CHEMBL4848921)
Affinity DataIC50:  3.02E+3nMAssay Description:Inhibition of eIF2alpha (unknown origin) assessed as eIF2alpha phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Hibercell

Curated by ChEMBL
LigandPNGBDBM50570949(CHEMBL4848921)
Affinity DataIC50:  159nMAssay Description:Inhibition of human His-tagged PERK expressed in Escherichia coli assessed as eIF2alpha phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed