BDBM50571206 CHEMBL4861930

SMILES OC1(CSC(=S)N1Cc1ccncc1)c1ccccc1

InChI Key InChIKey=RPAZLTQZYXMTQP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50571206   

TargetGlycogen synthase kinase-3 beta(Human)
Ohio University

Curated by ChEMBL
LigandPNGBDBM50571206(CHEMBL4861930)
Affinity DataIC50: 102nMAssay Description:Inhibition of human GSK-3beta preincubated for 3 hrs followed by ATP and substrate addition measured by serial dilution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Ohio University

Curated by ChEMBL
LigandPNGBDBM50571206(CHEMBL4861930)
Affinity DataIC50: 370nMAssay Description:Inhibition of human GSK-3beta incubated with substrate in presence of ATP measured by serial dilution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 alpha(Human)
Ohio University

Curated by ChEMBL
LigandPNGBDBM50571206(CHEMBL4861930)
Affinity DataIC50: 370nMAssay Description:Inhibition of human wild type GSK-3beta incubated with substrate in presence of ATP measured by serial dilution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Ohio University

Curated by ChEMBL
LigandPNGBDBM50571206(CHEMBL4861930)
Affinity DataIC50: 1.21E+5nMAssay Description:Inhibition of human GSK-3beta C199A mutant incubated with substrate in presence of ATP measured by serial dilution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed