BDBM50571250 CHEMBL4847629

SMILES CC(C)C(C(=O)Nc1ccc2n(C)cnc2c1)c1ccc([nH]c1=O)-c1ccc2cccc(F)c2c1

InChI Key InChIKey=VFQCDAIXGKKBRB-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50571250   

TargetProstaglandin E2 receptor EP3 subtype(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50571250(CHEMBL4847629)
Affinity DataKi:  3.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor expressed in CHO cells by radioligand competition binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50571250(CHEMBL4847629)
Affinity DataIC50: 6.30nMAssay Description:Antagonist activity at human EP3 receptor expressed in CHO cells by cell based cAMP functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed