BDBM50571752 CHEMBL4849247

SMILES COC(=O)c1ccc2c(c1)[nH]c1c(NC(=O)C3CC3)nccc21

InChI Key InChIKey=ACRYPFBNYMEDTL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50571752   

TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571752(CHEMBL4849247)
Affinity DataIC50: 70nMAssay Description:Inhibition of GSK3-beta (unknown origin) incubated for 60 mins by ATP-Glo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571752(CHEMBL4849247)
Affinity DataIC50: 71nMAssay Description:Inhibition of human full length GSK3beta expressed in baculovirus in Sf9 insect cells using YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE as substrate by ADP-Glo kin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2022
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571752(CHEMBL4849247)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50571752(CHEMBL4849247)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated with enzyme for 20 mins followed by substrate addition and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed