BDBM50572641 CHEMBL4854435

SMILES Cc1ccc(Oc2ccc(cc2)C(=O)C(=O)Nc2ccc3n(C)ccc3c2)cc1

InChI Key InChIKey=YREHRYQXOSORMH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50572641   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50572641(CHEMBL4854435)
Affinity DataEC50:  60nMAssay Description:Positive allosteric modulator activity at human alpha7 nAChR expressed in Flp-In-HEK293 cells co-expressing RIC-3 assessed as potentiation of PNU2829...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed