BDBM50573098 CHEMBL4873493

SMILES CCN1CCC2(C[C@@H]2C(=O)N[C@@H](CCCCCC(=O)CC)c2ncc(o2)-c2cc3cccnc3cc2OC)CC1

InChI Key InChIKey=XRYBEZILSSFQFH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50573098   

TargetHistone deacetylase 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50573098(CHEMBL4873493)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant FLAG-tagged HDAC1 expressed in HEK293F cells incubated for 30 mins by Fluor De Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50573098(CHEMBL4873493)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant FLAG-tagged HDAC3 expressed in HEK293F cells incubated for 30 mins by Fluor De Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50573098(CHEMBL4873493)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human recombinant FLAG-tagged HDAC2 expressed in Sf9 cells incubated for 30 mins by Fluor De Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50573098(CHEMBL4873493)
Affinity DataIC50: 83nMAssay Description:Inhibition of human HDAC6 incubated for 30 mins by Fluor De Lys assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed