BDBM50573461 CHEMBL4852489

SMILES [H][C@@]12CC[C@H](N1C(=O)[C@@H](CCC2)NC(=O)OC)c1ncc([nH]1)-c1ccc(cc1)-c1ccc(cc1)-c1cnc([nH]1)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OC)C(C)C

InChI Key InChIKey=UNBVOQXPDWSDET-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50573461   

TargetNonstructural protein 5A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50573461(CHEMBL4852489)
Affinity DataEC50:  0.0590nMAssay Description:Inhibition of HCV genotype 1b NS5A infected in HuH-7-Luc/Neo-ET cells assessed as reduction in viral replication measured by Luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50573461(CHEMBL4852489)
Affinity DataEC50:  0.673nMAssay Description:Inhibition of HCV genotype 1a NS5A infected in HuH-7-Luc/Neo-ET cells assessed as reduction in viral replication measured by Luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed