BDBM50573772 CHEMBL4858957

SMILES FC(F)(F)Oc1ccc(Nc2nc(Nc3ccccc3)ncc2Cl)cc1

InChI Key InChIKey=ATVUPPHKIBIGDN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50573772   

TargetDipeptidyl peptidase 1(Human)
Anhui Medical University

US Patent
LigandChemical structure of BindingDB Monomer ID 50573772BDBM50573772(CHEMBL4858957 | US12595236, Compound 12)
Affinity DataIC50: 2.08E+3nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2026
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Anhui Medical University

US Patent
LigandChemical structure of BindingDB Monomer ID 50573772BDBM50573772(CHEMBL4858957 | US12595236, Compound 12)
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of human recombinant Cathepsin C using H-Gly-Arg-AMC as substrate pretreated for 30 mins followed by substrate addition incubated for 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed