BDBM50573869 CHEMBL4556790

SMILES Cn1nccc1-c1ccc(C(=O)N[C@@H]2CNCC[C@H]2c2ccc(F)c(F)c2)c(F)c1

InChI Key InChIKey=PALTUSLCLFDFQQ-UHFFFAOYSA-N

Data  26 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 26 hits for monomerid = 50573869   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 4nMAssay Description:Inhibition of N-terminal GST-tagged human AKT1 (104 to 408 residues) expressed in baculovirus infected Sf21 cells incubated for 1 hr in presence of A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 28nMAssay Description:Inhibition of AKT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 98nMAssay Description:Inhibition of N-terminal GST-tagged human AKT2 (120 to 481 residues) expressed in baculovirus infected Sf21 cells incubated for 1 hr in presence of A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase beta-1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 229nMAssay Description:Inhibition of P70S6K (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 354nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetProtein kinase C theta type(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 629nMAssay Description:Inhibition of PKCtheta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 756nMAssay Description:Inhibition of RSK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of SGK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetProtein kinase C eta type(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PKCeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetTestis-specific serine/threonine-protein kinase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TSSK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ABL (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRibosomal protein S6 kinase alpha-5(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of MSK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PDK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A5(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50573869(CHEMBL4556790)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP3A5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed