BDBM50574115 CHEMBL4857884

SMILES FC(F)(F)c1cc(nc(Nc2ccccc2)n1)-c1ccco1

InChI Key InChIKey=FDDSVPRLHYUMHF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50574115   

TargetToll-like receptor 8(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50574115(CHEMBL4857884)
Affinity DataIC50: 7.70E+4nMAssay Description:Negative modulator activity at human TLR8 expressed in HEK-Blue hTLR8 cells assessed as inhibition of TL8-506 stimulated NF-kappaB activation preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed