BDBM50574118 CHEMBL4878029

SMILES Oc1cccc(CNc2nc(cc(n2)C(F)(F)F)-c2ccco2)c1

InChI Key InChIKey=DPDHKYDUAATJLO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50574118   

TargetToll-like receptor 8(Human)
University of Ljubljana

Curated by ChEMBL
LigandPNGBDBM50574118(CHEMBL4878029)
Affinity DataIC50: 2.30E+4nMAssay Description:Negative modulator activity at human TLR8 expressed in HEK-Blue hTLR8 cells assessed as inhibition of TL8-506 stimulated NF-kappaB activation preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed