BDBM50574162 CHEMBL368698

SMILES O=S(=O)(c1ccccc1)n1ccc2c(OCCNCc3ccccc3)cccc12

InChI Key InChIKey=WWCIYLXNRVTMRO-UHFFFAOYSA-N

Data  1 KI  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50574162   

Target5-hydroxytryptamine receptor 6(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50574162(CHEMBL368698)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in CHO-K1 membrane incubated for 60 mins by solid scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetCholinesterase(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50574162(CHEMBL368698)
Affinity DataIC50:  1.61E+3nMAssay Description:Inhibition of BuChE in human plasma using BTC as substrate preincubated with enzyme for 5 mins followed by substrate addition for 5 mins by Ellman's ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCholinesterase(Horse)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50574162(CHEMBL368698)
Affinity DataIC50:  473nMAssay Description:Inhibition of equine serum BuChE using BTC as substrate preincubated with enzyme for 5 mins followed by substrate addition for 5 mins by Ellman's met...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)