BDBM50574363 CHEMBL4848779

SMILES CN1C(=O)Cc2cc(ccc12)C(=O)Nc1cc(ccc1N)-c1cccs1

InChI Key InChIKey=DITFNMBCRZRUJF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50574363   

TargetHistone deacetylase 1(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574363(CHEMBL4848779)
Affinity DataIC50: 5nMAssay Description:Inhibition of HDAC1 (unknown origin) preincubated for 10 mins followed by tripeptide substrate addition and measured after 60 mins by fluorescence mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50574363(CHEMBL4848779)
Affinity DataIC50: 10nMAssay Description:Inhibition of human HDAC2 preincubated for 10 mins followed by tripeptide substrate addition and measured after 60 mins by fluorescence microplate re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed