BDBM50575251 CHEMBL4852401

SMILES CCn1c(CO)nn(-c2cc(O[C@@H](C)C(F)(F)F)c3c(Oc4c(F)ccc(OC)c4Cl)nccc3c2)c1=O

InChI Key InChIKey=OXGJMPFCJVCOPC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50575251   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50575251(CHEMBL4852401)
Affinity DataIC50: 0.300nMAssay Description:Inhibition of human DHODH using dihydroorotate as substrate and CoQ6 as co-substrate by DCIP dye based spectrophotometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed