BDBM50575254 CHEMBL4851260

SMILES CCn1c(CO)nn(-c2nc(O[C@@H](C)C(F)(F)F)c3c(Nc4c(F)cccc4Cl)nncc3c2F)c1=O

InChI Key InChIKey=GFRIMQHCZPUTQX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50575254   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50575254(CHEMBL4851260)
Affinity DataIC50: 0.380nMAssay Description:Inhibition of human DHODH using dihydroorotate as substrate and CoQ6 as co-substrate by DCIP dye based spectrophotometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed