BDBM50575331 CHEMBL4868242
SMILES Cc1c(cccc1-c1ccc(NC(=O)c2c(F)cccc2F)cc1)-c1nn(C)c(=O)o1
InChI Key InChIKey=ZKAHFFVNALZECX-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50575331
Affinity DataIC50: 11nMAssay Description:Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...More data for this Ligand-Target Pair
TargetCalcium release-activated calcium channel protein/Stromal interaction molecule 1(Homo sapiens (Human))
Lupin
Curated by ChEMBL
Lupin
Curated by ChEMBL
Affinity DataIC50: 76nMAssay Description:Inhibition of Orai1/STIM1 (unknown origin) expressed in HEK293 cells assessed as reduction in Ca2+-release activated Ca2+ entry current by manual pat...More data for this Ligand-Target Pair
Affinity DataIC50: 695nMAssay Description:Inhibition of TNF-alpha in thapsigargin stimulated human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 183nMAssay Description:Inhibition of IL2 in thapsigargin stimulated human whole bloodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Lupin
Curated by ChEMBL
Lupin
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERG by FLIPR TETRA methodMore data for this Ligand-Target Pair