BDBM50575851 CHEMBL4439422

SMILES OC(=O)CCc1nc(c(o1)-c1ccccc1)-c1ccccc1Cl

InChI Key InChIKey=KCXXPIVBPKZWHN-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50575851   

TargetNuclear receptor subfamily 4 group A member 2(Human)
Ludwig-Maximilians-University of Munich

Curated by ChEMBL
LigandPNGBDBM50575851(CHEMBL4439422)
Affinity DataIC50: 1.40E+4nMAssay Description:Inverse agonist activity at Gal4-fused human full length Nurr1 LBD transfected in HEK293T cells assessed as suppression of Nurr1 activation incubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50575851(CHEMBL4439422)
Affinity DataEC50:  3.60E+4nMAssay Description:Agonist activity at human RXRalpha transfected in human HEK293T cells co-expressing pFR/pRL-Luc incubated for 14 to 16 hrs by hybrid reporter gene as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-beta(Human)
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM50575851(CHEMBL4439422)
Affinity DataEC50:  4.80E+4nMAssay Description:Agonist activity at human RXRbeta transfected in human HEK293T cells co-expressing pFR/pRL-Luc incubated for 14 to 16 hrs by hybrid reporter gene ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2022
Entry Details Article
PubMed