BDBM50576575 CHEMBL4860567
SMILES Cc1n[nH]c2ccc3nc(-c4c[nH]nc4C(F)(F)F)c4CC(CCc4c3c12)C#N
InChI Key InChIKey=PCJQDNKWCRZDES-QGOAFFKASA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50576575
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Purdue University
Curated by ChEMBL
Purdue University
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human FLT3 ITD mutant using EAIYAAPFAKKK as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after 2 hrs by...More data for this Ligand-Target Pair
Affinity DataIC50: 333nMAssay Description:Inhibition of CDK2/Cyclin A1 (unknown origin) at 1 uM using histone H1 as substrate preincubated for 20 mins followed by 33P-ATP addition and measure...More data for this Ligand-Target Pair