BDBM50576893 CHEMBL4865331

SMILES CC(C)n1cnnc1-c1ccc2[nH]nc(-c3cc(cc(c3)-n3cnc(c3)C3CC3)N3CCOCC3)c2c1

InChI Key InChIKey=AGQOBTLSVLYGGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50576893   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50576893(CHEMBL4865331)
Affinity DataIC50: 75nMAssay Description:Inhibition of human full length recombinant ASK1 using STK-Substrate-3 biotin as substrate in presence of ATP measured after 2 hrs by HTRP kinase ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed