BDBM50577126 CHEMBL4877753

SMILES COc1ccc(C[C@H](NC(=O)[C@H](C)NC(=O)n2c3ccccc3c3ccccc23)C(=O)N[C@@H](Cc2ccccc2)C(=O)[C@@]2(C)CO2)cc1

InChI Key InChIKey=NRMAIIYBLXTPGE-RIIJTAHDSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50577126   

TargetProteasome subunit beta type-5(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50577126(CHEMBL4877753)
Affinity DataIC50:  36nMAssay Description:Inhibition of chymotrypsin-like activity of human 20s proteasome beta 5c subunit using suc-WLA-AMC as flurogenic substrate preincubated for 15 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50577126(CHEMBL4877753)
Affinity DataIC50:  61nMAssay Description:Inhibition of human proteasome subunit beta-5i chymotrypsin like activity using SUC-ANW-AMC as flurogenic substrate preincubated for 15 mins followed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed