BDBM50577130 CHEMBL4846410

SMILES COC1CCN(CC1)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccc(OC)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1

InChI Key InChIKey=DEJDODIYNAEWHY-OYJHBXMHSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50577130   

TargetProteasome subunit beta type-8(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50577130(CHEMBL4846410)
Affinity DataIC50:  19nMAssay Description:Inhibition of human proteasome subunit beta-5i chymotrypsin like activity using SUC-ANW-AMC as flurogenic substrate preincubated for 15 mins followed...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit alpha type-1(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50577130(CHEMBL4846410)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of caspase-like activity of human proteasome beta-1c subunit using SUC-LLE-AMC as flurogenic substrate preincubated for 15 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50577130(CHEMBL4846410)
Affinity DataIC50:  74nMAssay Description:Inhibition of chymotrypsin-like activity of human 20s proteasome beta 5c subunit using suc-WLA-AMC as flurogenic substrate preincubated for 15 mins f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed