BDBM50577140 CHEMBL4871044

SMILES C\C(CC[C@H](O)C(C)(C)O)=C/CC\C(C)=C\Cc1c(O)cc(C)c(C(O)=O)c1O

InChI Key InChIKey=CWSUETWLMHLISD-LHDPSMIPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50577140   

TargetBeta-secretase 1(Homo sapiens (Human))
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50577140(CHEMBL4871044)
Affinity DataIC50:  3.44E+4nMAssay Description:Inhibition of BACE1 (unknown origin) using Rh-EVNNLDAEFK fluorogenic peptide as substrate incubated for 3 hrs by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Meiji Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50577140(CHEMBL4871044)
Affinity DataIC50:  5.33E+4nMAssay Description:Inhibition of self-induced aggregation amyloid beta (1 to 40) (unknown origin) incubated for 24 hrs by Thioflavin T based fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed