BDBM50577639 CHEMBL4877727

SMILES CNC(=O)c1cc(cs1)-n1ncc2cc(Nc3c(F)cccc3Cl)ncc12

InChI Key InChIKey=YFZJFPUOKUFWQU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50577639   

TargetMitogen-activated protein kinase 10(Human)
Reaction Biology

Curated by ChEMBL
LigandPNGBDBM50577639(CHEMBL4877727)
Affinity DataIC50: 2nMAssay Description:Inhibition of JNK3alpha1 (unknown origin) using biotinylated FL-ATF-2 as substrate measured after 22 mins by homogeneous time-resolved fluorescence a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Reaction Biology

Curated by ChEMBL
LigandPNGBDBM50577639(CHEMBL4877727)
Affinity DataIC50: 57nMAssay Description:Inhibition of p38 alpha (unknown origin) using biotinylated FL-ATF-2 as substrate measured after 22 mins by homogeneous time-resolved fluorescence an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Reaction Biology

Curated by ChEMBL
LigandPNGBDBM50577639(CHEMBL4877727)
Affinity DataIC50: 74nMAssay Description:Inhibition of JNK2 (unknown origin) using biotinylated FL-ATF-2 as substrate measured after 22 mins by homogeneous time-resolved fluorescence analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Reaction Biology

Curated by ChEMBL
LigandPNGBDBM50577639(CHEMBL4877727)
Affinity DataIC50: 260nMAssay Description:Inhibition of JNK1 (unknown origin) using biotinylated FL-ATF-2 as substrate measured after 22 mins by homogeneous time-resolved fluorescence analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed