BDBM50577748 CHEMBL4870497

SMILES CCOCc1nc(=O)c(C(=O)N2CC[C@@H](C2)c2ccccc2)c(O)n1-c1c(OC)cccc1OC

InChI Key InChIKey=KKVOZQKVYSKADL-SFHVURJKSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50577748   

TargetApelin receptor(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50577748(CHEMBL4870497)
Affinity DataEC50:  0.440nMAssay Description:Agonist activity at human APJ receptor expressed in HEK293T cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetApelin receptor(Homo sapiens (Human))
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50577748(CHEMBL4870497)
Affinity DataEC50:  0.400nMAssay Description:Agonist activity at human APJ expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production incubated for 60 mins by fluor...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetApelin receptor(Rattus norvegicus)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50577748(CHEMBL4870497)
Affinity DataEC50:  0.610nMAssay Description:Agonist activity at rat APJ receptor expressed in HEK293T cells assessed as compound stimulated inhibition of forskolin stimulated cAMP production in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed