BDBM50578155 CHEMBL4873581

SMILES NC(=O)c1c(nc([C@@H]2CCCCN2C(=O)C=C)n1N)-c1ccc(cc1)C(=O)Nc1cc(I)ccn1

InChI Key InChIKey=XBDYOLRJDCQKGB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50578155   

TargetTyrosine-protein kinase BTK(Human)
Henan Normal University

Curated by ChEMBL
LigandPNGBDBM50578155(CHEMBL4873581 | US12291516, Example 89)
Affinity DataIC50: 6.10nMAssay Description:Inhibition of full-length N-terminal GST tagged BTK (2 to 659 residues) (unknown origin) expressed in Sf21 insect cells using NH2-ETVYSEVRK-biotin as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Human)
Henan Normal University

Curated by ChEMBL
LigandPNGBDBM50578155(CHEMBL4873581 | US12291516, Example 89)
Affinity DataIC50: 6.12nMAssay Description:Reagent and Procedure by Reaction Biology Corporation:Base Reaction buffer; 20 mM Hepes (pH 7.5), 10 mM MgCl2, 1 mM EGTA, 0.02%. Brij35, 0.02 mg/ml B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2025
Entry Details
US Patent