BDBM50578291 CHEMBL4854112

SMILES Cc1c(cccc1C(F)(F)Oc1cc(OCc2ccnc(c2)C#N)c(CN[C@@H]2C(O)O[C@H](CO)[C@@H](O)[C@@H]2O)cc1Cl)-c1ccc2OCCOc2c1

InChI Key InChIKey=TUOSAPKOJRLJAP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50578291   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50578291(CHEMBL4854112)
Affinity DataIC50: 10nMAssay Description:Inhibition of PD-1/PD-L1 interaction (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetProgrammed cell death 1 ligand/protein 1(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM50578291(CHEMBL4854112)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of PD-1/PD-L1 interaction in human Jurkat T cells expressing PD-1 cocultured with CHO cells expressing PD-Ll/TCR assessed as activation of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed