BDBM50579164 CHEMBL4858091

SMILES Oc1ccc(cc1)-c1ccc2c(Nc3ccnc(c3)-c3cc(F)ccc3F)ccnc2c1

InChI Key InChIKey=LZXQSGOKGXBVLB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50579164   

TargetTGF-beta receptor type-1(Homo sapiens (Human))
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50579164(CHEMBL4858091)
Affinity DataIC50:  16nMAssay Description:Inhibition of human TGFbeta receptor 1 in human HEK293 cells preincubated for 24 hrs followed by addition of TGFbeta1 and measured after 24 hrs by lu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed