BDBM50579175 CHEMBL4850787
SMILES CN(C)CCn1cc(cn1)-c1ccc2c(Nc3ccnc(c3)-c3cc(F)ccc3F)ccnc2c1
InChI Key InChIKey=MPUBMJCSEANNKB-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50579175
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
University Of Arkansas For Medical Sciences
Curated by ChEMBL
University Of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 121nMAssay Description:Inhibition of recombinant human GST-tagged MAP4K4 expressed in baculovirus expression system using 5-FAM-KRELVEPLTPSGEAPNQALLR-CONH2 substrate preinc...More data for this Ligand-Target Pair
TargetTGF-beta receptor type-1(Homo sapiens (Human))
University Of Arkansas For Medical Sciences
Curated by ChEMBL
University Of Arkansas For Medical Sciences
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human TGFbeta receptor 1 in human HEK293 cells preincubated for 24 hrs followed by addition of TGFbeta1 and measured after 24 hrs by lu...More data for this Ligand-Target Pair