BDBM50579183 CHEMBL4854949

SMILES CS(=O)(=O)c1ccc(/C=C/C2CC(Nc3ccnc(-c4cc(F)ccc4F)c3)=CC=N2)cc1

InChI Key InChIKey=CRDUMPVQRUQRQG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50579183   

TargetTGF-beta receptor type-1(Human)
University of Arkansas For Medical Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579183BDBM50579183(CHEMBL4854949)
Affinity DataIC50: 13nMAssay Description:Inhibition of human TGFbeta receptor 1 in human HEK293 cells preincubated for 24 hrs followed by addition of TGFbeta1 and measured after 24 hrs by lu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed