BDBM50579370 CHEMBL4870348

SMILES CNC(=O)CCCCCCCn1nc(-c2ccc3oc(N)nc3c2)c2c(N)ncnc12

InChI Key InChIKey=ZLJFPDJEZABMJB-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50579370   

TargetHistone deacetylase 1(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50579370(CHEMBL4870348)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50579370(CHEMBL4870348)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of HDAC2 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50579370(CHEMBL4870348)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of mTOR (unknown origin) using U-Light-4E-BP1 peptide as a substrate in the presence of ATP incubated for 30 mins by Lance ultra assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50579370(CHEMBL4870348)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50579370(CHEMBL4870348)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of HDAC3 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
South China University of Technology

Curated by ChEMBL
LigandPNGBDBM50579370(CHEMBL4870348)
Affinity DataIC50: 334nMAssay Description:Inhibition of HDAC8 (unknown origin) using Ac-peptide as a substrate pretreated for 15 mins followed by substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed