BDBM50579390 CHEMBL1571747

SMILES COC(=O)Cc1cc(O)n(n1)-c1nc2ccccc2[nH]1

InChI Key InChIKey=WXZOESBZOHFYIS-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50579390   

TargetLysine-specific demethylase 4B(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50579390(CHEMBL1571747)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human KDM4B (1 to 347 residues) catalytic domain measured formaldehyde dehydrogenase (FDH)-coupled fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysine-specific demethylase 4A(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50579390(CHEMBL1571747)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human KDM4A (1 to 359 residues) catalytic domain measured formaldehyde dehydrogenase (FDH)-coupled fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysine-specific demethylase 4D(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50579390(CHEMBL1571747)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human KDM4D (1 to 378 residues) catalytic domain measured formaldehyde dehydrogenase (FDH)-coupled fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysine-specific demethylase 4C(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50579390(CHEMBL1571747)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human KDM4C (1 to 347 residues) catalytic domain measured formaldehyde dehydrogenase (FDH)-coupled fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysine-specific demethylase 4E(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50579390(CHEMBL1571747)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human KDM4E (1 to 378 residues) catalytic domain measured formaldehyde dehydrogenase (FDH)-coupled fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetLysine-specific demethylase 4E(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50579390(CHEMBL1571747)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 preincubated for 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2022
Entry Details Article
PubMed
TargetLysine-specific demethylase 4E(Human)
St. Jude Children'S Research Hospital

Curated by ChEMBL
LigandPNGBDBM50579390(CHEMBL1571747)
Affinity DataIC50: 5.81E+5nMAssay Description:Inhibition of N-terminal His6-tagged KDM4E (1 to 337 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3)-R3 preincubated for 10 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2022
Entry Details Article
PubMed