BDBM50579553 CHEMBL4860819

SMILES COc1nn(C)cc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H](C)C(F)(F)F

InChI Key InChIKey=VOAVBNDXAXMDDN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50579553   

LigandPNGBDBM50579553(CHEMBL4860819)
Affinity DataIC50: 3nMAssay Description:Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2022
Entry Details Article
PubMed
LigandPNGBDBM50579553(CHEMBL4860819)
Affinity DataIC50: 17nMAssay Description:Inhibition of full-length human ASK1 expressed in HEK293T cells assessed as reduction in autophosphorylation of ASK1 at T383 residue incubated for 1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2022
Entry Details Article
PubMed
LigandPNGBDBM50579553(CHEMBL4860819)
Affinity DataIC50: 17nMAssay Description:Inhibition of ASK1 (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed