BDBM50579564 CHEMBL4866921
SMILES COc1nn(cc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H](C)C(F)(F)F)-c1cnccn1
InChI Key InChIKey=DGQZOGNJUMXTRN-NSHDSACASA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50579564
Affinity DataIC50: 58nMAssay Description:Inhibition of full-length human ASK1 expressed in HEK293T cells assessed as reduction in autophosphorylation of ASK1 at T383 residue incubated for 1 ...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...More data for this Ligand-Target Pair