BDBM50579567 CHEMBL4874460

SMILES C[C@H](n1cnnc1-c1cccc(NC(=O)c2cccc3N(C)CCOc23)n1)C(F)(F)F

InChI Key InChIKey=NCQUIDLJDDHLGM-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50579567   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen

Curated by ChEMBL

LigandBDBM50579567(CHEMBL4874460)Copy SMILESCopy InChI

Affinity DataIC50: 7nMAssay Description:Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/25/2022
Entry Details Article
Copy BDB DOIPubMed
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TargetMitogen-activated protein kinase kinase kinase 5(Human)
Biogen

Curated by ChEMBL

LigandBDBM50579567(CHEMBL4874460)Copy SMILESCopy InChI

Affinity DataIC50: 187nMAssay Description:Inhibition of full-length human ASK1 expressed in HEK293T cells assessed as reduction in autophosphorylation of ASK1 at T383 residue incubated for 1 ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/25/2022
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL