BDBM50579712 CHEMBL5085444

SMILES COc1ccc2CCCN(CCC\C=C/c3cccc4NC(=O)C[C@@H](C)Nc34)c2c1

InChI Key InChIKey=VBTDHMQUNCGCSZ-UHFFFAOYSA-N

Data  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50579712   

TargetCREB-binding protein(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50579712(CHEMBL5085444)
Affinity DataKd:  316nMAssay Description:Binding affinity to human CREBBP bromodomain expressed in Escherichia coli BL21 (DE3)-RILMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetCREB-binding protein(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50579712(CHEMBL5085444)
Affinity DataKd:  329nMAssay Description:Binding affinity to human CREBBP bromodomain expressed in Escherichia coli BL21 (DE3)-RIL assessed as dissociation constant by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50579712(CHEMBL5085444)
Affinity DataKd:  1.17E+3nMAssay Description:Binding affinity to human BRD4 bromodomain 1 assessed as dissociation constant by ITC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50579712(CHEMBL5085444)
Affinity DataKd:  2.03E+3nMAssay Description:Binding affinity to human BRD4 bromodomain 1 assessed as dissociation constant by NMR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed